DiagnosticPerformanceof a Commercial Assay for Thyrotropin ,
نویسندگان
چکیده
Ref. RF value, Mean, Int. No. of Mean, mt. No. of nt. unlts/mL unlts/mL runs unlts/mL runs w,oa 100 253 3 110 11 CDCb 100
منابع مشابه
Ten commercial kits compared for assay of thyrotropin in the normal and thyrotoxic range.
I developed a standard procedure for assessing sensitivity, intra-assay precision, parallelism of sample dilutions, and assay drift, using a single trial assay kit. I used this to compare the performance of 10 commercial kits with an in-house radioimmunoassay for human thyrotropin. No one kit stood out as clearly superior overall. Differences in calibration between kits were evident in a compar...
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Thyroid Stimulating Hormone Receptor (TSH-R) autoantibodies are the main cause of Graveschr('39') disease and its external thyroid manifestations such as ophtalmopathy and dermatopathy. These antibodies are functionally different and are commonly called TSH receptor antibodies (TRAbs). In fact, TRAbs are a set of autoantibodies including TSHR-stimulating antibodies (TSAbs), TSHR- blocking antib...
متن کاملHigh sensitivity, homogeneous particle-based immunoassay for thyrotropin (Multipact).
We describe the first homogeneous, nonradioactive, high-sensitivity assay for human thyrotropin (TSH). The assay is based on particle immunoassay techniques, wherein 800-nm particles form the basis for the immunochemistry, delivery, and the detection technologies, respectively. Our assay also is the first to involve the use of fragmented monoclonal antibodies (to eliminate serum interferences) ...
متن کاملHow Rapid Is “ Rapid ” ?
Once again, lack of judicious editorial constraint on the part of Clinical Chemistry in allowing the inappropriate use of terms such as “more rapid,” “more efficient,” and “more prompt” to describe a new modification of pre-existing methodologies has struck a levance”chord in us (1). In this instance, the article in question describes a simultaneous radioimmunoassay of thyroxine (T4) and thyrot...
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تاریخ انتشار 2004